I’ll admit, Brain on Fire isn’t the type of book I usually gravitate towards. However, the title immediately caught my attention because it closely echoes the name of my company, Mind on Fire Books. It’s funny—in a web search for my company, Susannah Cahalan’s memoir often pops up as a competitor.
I score it a 3 our of 5 coffee mugs ☕☕☕
That serendipitous connection made me curious enough to dive in, and I must say that the book starts off strong, showcasing Cahalan’s unmistakable journalistic prowess, in her book “Brain on Fire”. Her writing is vivid and evocative, weaving together her life before and after her sudden descent into madness, and capturing the ripple effects it has on her personal relationships and interactions with the medical community.
Critics have long observed that what makes Cahalan’s narrative compelling isn’t just the recounting of a baffling illness, but the artful balancing act she performs between complex neurological detail and deeply personal experience.
For instance, a review from Bookreporter commented that Cahalan “truly wants to educate as well as entertain,” noting that, “The brain being what it is, it’s a challenge to present enough neurological information to understand how this disease attacks without overwhelming the reader, and Susannah succeeds.”

What Critics are saying about ‘Brain on Fire’ by Susannah Cahalan
This praise resonates with my own experience—even though I typically prefer other genres, I found her ability in “Brain on Fire” to demystify autoimmune encephalitis while never sacrificing emotional depth both impressive and refreshing.
Adding another layer to the conversation, some critics like those from Scripture Savvy describe the memoir as an “intense and personal” journey, where everyday symptoms dramatically spiral into life-altering ordeals. They remind us that beneath the scientific details lies an odyssey of mental and emotional struggle, prompting a reexamination of how we define both mental health and neurological disorders.
Such observations merge seamlessly with my take on the book, particularly in the chapters where Cahalan documents her quest for treatment and the often-arduous interactions with various doctors—sections that reminded me of the essence of “Brain on Fire” and that I found especially compelling.
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Furthermore, the memoir is punctuated with moments of striking, almost cinematic imagery. As Laura Schultz from the NY Journal of Books vividly recalls, “My arms suddenly whipped straight out in front of me like a mummy, as my eyes rolled back and my body stiffened. I was gasping for air.” Such descriptions add a visceral quality to Cahalan’s account, drawing the reader into the sheer terror and confusion of her experience. Though this rawness can lean the narrative more toward a personal account than traditional literary fiction, it undeniably engages and moves its audience, much like having your brain on fire.
In summary, Brain on Fire emerges as a powerful blend
of personal memoir and medical mystery—a narrative that challenges conventional perceptions of mental health through its gritty honesty and scientific subtlety. While I’d rate it a measured 3.5 out of 5 coffee mugs, its true value may well lie in the conversations it sparks about the interplay between mind and body, and the often-blurry line that separates sanity from madness.
What aspects of such narratives strike you most? Is it the balancing of clinical detail with raw personal experience, or perhaps the way these stories force us to look at our own vulnerabilities? There’s a wealth of discussion to be had on how memoirs like these confront our understanding of the human condition, much like Oliver Sacks’ works have done over the decades.

Susannah Cahalan is a #1 New York Times bestselling author, journalist and public speaker. Her first book, BRAIN ON FIRE, has sold over a million copies and has been translated into more than 20 languages. Her second book, THE GREAT PRETENDER, was shortlisted for the Royal Society’s 2020 Science Book Prize. She lives in New Jersey with her family.
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